Based on evidence and experience, countries worldwide are adding the option of DMPA-SC self-injection to their contraceptive method mix.
Self-injection has the potential to reduce access-related barriers for women, increase contraceptive continuation rates, and enhance women’s autonomy. There are strong data that women, including women in low-resource settings, can self-administer DMPA-SC safely and effectively, and that they like doing so.
Often women are unable to access self-injectable contraception because of gaps in provider training, supply chains, medical waste management, and other issues. D-Prize is helping to address these gaps by funding aspiring entrepreneurs to expand access to DMPA-SC in low-income countries.
Each D-Prize award winner will receive up to US$20,000 to launch a nonprofit or social venture tackling a DMPA-SC access gap. Applicants should be entrepreneurial and ready to commit full-time to their venture if the pilot succeeds. Organizations that apply should be entirely new or at a very early stage (under 18 months old or raised less than US$30,000).
2026 deadlines Early: May 17 | Regular: June 7 | Extension: June 28
The Advancing Injectable Markets for Sustainability (AIMS) project provides free data-driven technical assistance (TA), coordination, resources, and tools to ensure that women and girls have increased access to DMPA-SC and self-injection as part of an expanded range of contraceptive methods, delivered through informed choice programming.
Partners can access TA by submitting a request to the AIMS team at FPoptions@path.org.
PATH has developed this comprehensive suite of scientific communications materials to support evidence-based introduction and scale-up of DMPA-SC and self-injection (SI).
This resource provides a high-level summary of the current state of self-injection policy development, implementation, and monitoring in each of the Injectables Access Collaborative’s 11 focus countries: Benin, DRC, Ghana, Kenya, Madagascar, Malawi, Mozambique, Nigeria, Togo, Uganda, and Zambia. The policy cycle landscape (i.e., policy development, implementation, and monitoring) features an overview of the enabling environment for self-injection in each country, including general self-injection and self-care policies, as well as local authorizations for task-sharing/task-shifting. The information is current as of Quarter 2, 2025.
PATH has compiled a list featuring presentations, posters, and events on the topic of DMPA-SC, including self-injection and self-care, to be featured at the International Conference on Family Planning on 3-6 November 2025. The list linked below includes nearly 70 abstracts highlighting the latest DMPA-SC research and implementation experience from a diverse array of partner organizations.
In this special issue, the Gates Foundation invested in a coordinated effort to understand how self-injection can be best introduced into different markets across six countries (Kenya, Uganda, Nigeria, Malawi, Pakistan, and India). Within this effort, the Gates Foundation sought assistance from the University of California San Francisco to launch the Self-Injection Learning Exchange with two goals: (1) Aggregate and synthesize grantee learnings and (2) Share resources and facilitate discussions of emergent findings. Made up of twelve different grantees and two funders, the Gates Foundation and the Children’s Investment Fund (who have jointly funded self-injection investments), the Learning Exchange synthesizes findings and progress across 12 investments into a quarterly slide deck, meets quarterly with funders and grantees, and has organized this special supplement.
The objective of this supplement is to capitalize on this unique opportunity to reflect across a set of coordinated investments, to bring together diverse and complementary studies on self-injection, and to offer commentary related to lessons learned from this coordinated effort.
Institutional author(s): Gates Foundation
Publication date: 2025
This medication use evaluation assessed the impact of an initiative at North Florida/South Georgia Veterans Health System (NFSGVHS) in the United States to offer patients self-administered DMPA-SC. A retrospective chart review of electronic health records was conducted for patients who received ≥ 1 outpatient prescription for DMPA-SC from June 1, 2022 to July 1, 2023. Forty patients initiated self-administered DMPA-SC. A subgroup of patients were contacted via telephone as a follow-up to determine if there were unmet needs for ongoing contraceptive care. The uptake in prescribing suggests that clinicians and patients have embraced self-administration of DMPA-SC within the NFSGVHS.
Brown JM, Pardo KM. Federal Practitioner. 2025;42(8):314-317. doi:10.12788/fp.0614
This lesson is intended for health care providers learning to counsel family planning clients about DMPA-SC and self-injection in the context of informed choice. Developed by the Injectables Access Collaborative, the lesson incorporates key content from the more in-depth DMPA-SC self-injection empathy-based counseling developed by the PSI Delivering Innovation in Self-Care (DISC) project. The lesson can be incorporated into a comprehensive training on DMPA-SC or adapted as a refresher training for experienced providers.
This guidance from the World Health Organization (WHO) aims to provide a people-centred, evidence-based normative guideline that will support individuals, communities, and countries with quality health services and self-care interventions, based on PHC strategies, comprehensive essential service packages and people-centredness. The guidance includes a “strong” recommendation for self-administered injectable contraception, stating that this should be made available as an additional approach to deliver injectable contraception for individuals of reproductive age.